3. Thieves Oil
An essential oil blend created with cinnamon cloves, rosemary, lemon, and eucalyptus essential oils. It is noted for its antimicrobial, antiviral, and antifungal properties. Some users suggest that these combined benefits make it the best natural cold sore remedy for topical use. Apply 1 drop to the affected area up to 3 times daily, as needed. Note: Thieves Oil can be irritating to people with sensitive skin, so it is recommended that you not use more than 1 drop at a time.